| Monterrey (MTY) | 05:00 05:29 | en route delayed | Aeromexico Air Europa | AM 34 UX 2488 | 1 | 06 |
| Leipzig-Halle (LEJ) | 05:05 | planned | DHL Air | D08464 | CARG | |
| Buenos Aires (EZE) | 05:10 | en route | Air Europa Etihad Airways Aerolineas Argentinas | UX 42 EY 4396 AR 7358 | 2 | 06 |
| Lima (LIM) | 05:10 | en route | Air Europa Etihad Airways | UX 176 EY 4386 | 2 | 07 |
| Bagotville (YBG) | 05:11 | en route | Gestair | G5 | 2 | |
| Asuncion (ASU) | 05:20 | en route | Air Europa Etihad Airways Turkish Airlines | UX 24 EY 4381 TK 9391 | 1 | I108 |
| Tunis (TUN) | 05:20 | planned | Air Europa | UX1116 | 1 | I102 |
| Boston (BOS) | 05:40 | en route | Iberia British Airways Finnair Qatar Airways American Airlines | IB 6166 BA 4264 AY 5648 QR 6887 AA 8535 | 4S | 05 |
| Buenos Aires (EZE) | 05:40 | en route | Iberia British Airways Finnair Qatar Airways | IB 6856 BA 4252 AY 5376 QR 6919 | 4S | 03 |
| Sao Paulo (GRU) | 05:40 | en route | Iberia Cathay Pacific British Airways Qatar Airways Finnair LATAM Airlines El Al | IB 6824 CX 1840 BA 4246 QR 5087 AY 5380 LA 7107 LY 9200 | 4S | 08 |
| Santiago (SCL) | 05:40 | en route | Iberia Cathay Pacific British Airways Qatar Airways Finnair LATAM Airlines El Al | IB 6830 CX 1920 BA 4250 QR 5355 AY 5388 LA 5410 LY 9210 | 4S | 04 |
| Barcelona (BCN) | 05:45 | planned | Vueling | VY | 4S | |
| Bogota (BOG) | 05:55 | en route | Iberia LATAM Airlines British Airways Qatar Airways Finnair | IB 6590 LA 1604 BA 4234 QR 5348 AY 5390 | 4S | |
| Mexico City (MEX) | 06:00 | en route | Iberia British Airways Qatar Airways Finnair El Al | IB 6400 BA 4274 QR 5067 AY 5551 LY 9230 | 4S | 07 |
| Miami (MIA) | 06:05 | en route | American Airlines British Airways Finnair Iberia Royal Jordanian | AA 68 BA 1558 AY 4006 IB 4610 RJ 7033 | 4 | 06 |
| Montevideo (MVD) | 06:05 | en route | Iberia British Airways Qatar Airways | IB 6012 BA 4212 QR 5059 | 4S | 01 |
| Charlotte (CLT) | 06:10 | en route | American Airlines British Airways Finnair Iberia | AA 748 BA 1611 AY 4267 IB 4978 | 4 | 06 |
| New York (JFK) | 06:10 | en route | Iberia British Airways | IB 6250 BA 4270 | 4S | 02 |
| Lima (LIM) | 06:10 | en route | Wamos Air | EB6652 | 4S | |
| Las Palmas (LPA) | 06:25 | planned | Iberia Express | I23839 | 4 | 12 |
| Santo Domingo (SDQ) | 06:40 | en route | Iberia | IB6500 | 4S | 06 |
| Tenerife (TFS) | 06:45 | planned | Iberia Express | I23909 | 4 | 16 |
| Dubai (DWC) | 06:55 | en route | | | 1 | |
| Buenos Aires (EZE) | 06:55 | en route | Aerolineas Argentinas | AR1134 | 1 | 03 |